Algorithm-guided empirical tuberculosis treatment for people with advanced HIV (TB Fast Track): an open-label, cluster-randomized trial
Citation: Grant, A. D., Charalambous, S., Tlali, M., Karat, A. S., Dorman, S. E., Hoffmann, C. J., Johnson, S., Vassall, A., Churchyard, G. J., & Fielding, K. L. (2020). Algorithm-guided empirical tuberculosis treatment for people with advanced HIV (TB Fast Track): An open-label, cluster-randomised trial. The Lancet HIV, 7(1), e27–e37. https://doi.org/10.1016/S2352-3018(19)30266-8
Abstract: Tuberculosis, which is often undiagnosed, is the major cause of death among HIV-positive people. We aimed to test whether the use of a clinical algorithm enabling the initiation of empirical tuberculosis treatment by nurses in primary health-care clinics would reduce mortality compared with standard of care for adults with advanced HIV disease.
Author(s): The Lancet HIV
Region(s): SOUTH AFRICA
Resource Type: Journal Articles
Filed under: Co-infection, HIV, Journal Article, People living with HIV, Research, South Africa, TB and HIV, Treatment