Identification of subclinical tuberculosis in household contacts using exposure scores and contact investigations
Citation: Bekken, G.K., Ritz, C., Selvam, S. et al. Identification of subclinical tuberculosis in household contacts using exposure scores and contact investigations. BMC Infect Dis 20, 96 (2020). https://doi.org/10.1186/s12879-020-4800-y
Abstract: The goal of tuberculosis elimination put forward in the End TB Strategy prioritizes diagnosis and treatment of incipient and subclinical TB, recently defined by key stakeholders as “asymptomatic, early pre-clinical disease during which pathology evolves”. Regarded as indicative of a high risk of TB progression, considerable efforts have been made to identify these cases through exploration of biomarkers. The present study aimed to evaluate simple scoring systems for TB exposure as screening tools for subclinical TB, the only identifiable of the incipient and subclinical disease states, in a contact investigation (CI) setting of low HIV-prevalence.
Author(s): BMC Infectious Diseases
Resource Type: Journal Articles